Cytoplasmic dynein-1 motor domain bound to LIS1
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 8pqy
Q-score: 0.387
Singh K, Lau CK, Manigrasso G, Gama JB, Gassmann R, Carter AP
Science (2024) 383 pp. eadk8544-eadk8544 [ DOI: doi:10.1126/science.adk8544 Pubmed: 38547289 ]
- Magnesium ion (24 Da, Ligand)
- Platelet-activating factor acetylhydrolase ib subunit beta (46 kDa, Protein from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Cytoplasmic dynein-1 bound to lis1 (Complex from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Cytoplasmic dynein 1 heavy chain 1 (533 kDa, Protein from Homo sapiens)
Helical reconstruction of the human cardiac actin-tropomyosin-myosin complex in the rigor form
Resolution: 3.4 Å
EM Method: Helical reconstruction
Fitted PDBs: 8efi
Q-score: 0.435
Doran MH, Rynkiewicz MJ, Pavadai E, Bodt SML, Rasicci D, Moore JR, Yengo CM, Bullitt E, Lehman W
J Gen Physiol (2023) 155 [ DOI: doi:10.1085/jgp.202213274 Pubmed: 36459134 ]
- Actin, alpha cardiac muscle 1 (42 kDa, Protein from pig)
- Human cardiac myosin ii (Complex from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Tropomyosin alpha-1 chain (32 kDa, Protein from Homo sapiens)
- Human cardiac actin-tropomyosin-beta-myosin ii complex in the rigor form. (Complex)
- Human cardiac tropomyosin (Complex from Homo sapiens)
- Cardiac f-actin complex (Complex from Sus scrofa)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Myosin-7 (223 kDa, Protein from Homo sapiens)
Helical reconstruction of the human cardiac actin-tropomyosin-myosin loop 4 7G mutant complex
Resolution: 3.6 Å
EM Method: Helical reconstruction
Fitted PDBs: 8enc
Q-score: 0.405
Doran MH, Rynkiewicz MJ, Pavadai E, Bodt SML, Rasicci D, Moore JR, Yengo CM, Bullitt E, Lehman W
J Gen Physiol (2023) 155 [ DOI: doi:10.1085/jgp.202213274 Pubmed: 36459134 ]
- Actin, alpha cardiac muscle 1 (42 kDa, Protein from pig)
- Magnesium ion (24 Da, Ligand)
- Tropomyosin alpha-1 chain (32 kDa, Protein from Homo sapiens)
- Myosin-7 (222 kDa, Protein from Homo sapiens)
- Human cardiac actin-tropomyosin-beta-myosin ii complex with 7g loop 4 mutation (Complex)
- Human cardiac tropomyosin (Complex from Homo sapiens)
- Cardiac f-actin complex (Complex from Sus scrofa)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Human beta-cardiac myosin ii with seven (366-372) loop 4 residues mutated to glycine. (Complex from Homo sapiens)
13pf wildtype microtubule from recombinant human tubulin decorated with kinesin
Resolution: 3.6 Å
EM Method: Helical reconstruction
Fitted PDBs: 7sj8
Q-score: 0.428
LaFrance BJ, Roostalu J, Henkin G, Greber BJ, Zhang R, Normanno D, McCollum CO, Surrey T, Nogales E
PNAS (2022) 119 [ Pubmed: 34996871 DOI: doi:10.1073/pnas.2114994119 ]
- Magnesium ion (24 Da, Ligand)
- Tubulin beta-3 chain (51 kDa, Protein from Homo sapiens)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Tubulin alpha-1b chain (51 kDa, Protein from Homo sapiens)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- 13pf wildtype microtubule from recombinant human tubulin and decorated with kinesin (102 kDa, Complex from Homo sapiens)
Structure of the autoinhibited state of smooth muscle myosin-2
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7mf3
Q-score: 0.264
Heissler SM, Arora AS, Billington N, Sellers JR, Chinthalapudi K
Sci Adv (2021) 7 pp. eabk3273-eabk3273 [ Pubmed: 34936462 DOI: doi:10.1126/sciadv.abk3273 ]
- Phosphate ion (94 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Myosin-11 (229 kDa, Protein from Chicken)
- Myosin light polypeptide 6 (16 kDa, Protein from Chicken)
- Smooth muscle myosin-2 10s complex (531 kDa, Complex from Gallus gallus)
- Myosin regulatory light chain 2, smooth muscle major isoform (19 kDa, Protein from Chicken)
- Adenosine-5'-diphosphate (427 Da, Ligand)
Resolution: 10.2 Å
EM Method: Subtomogram averaging
Fitted PDBs: 7nep
Q-score: 0.088
Wang Z, Grange M, Wagner T, Kho AL, Gautel M, Raunser S
Cell (2021) 184 pp. 2135- [ Pubmed: 33765442 DOI: doi:10.1016/j.cell.2021.02.047 ]
- Tropomyosin (Complex from Mus musculus)
- Tropomyosin alpha-1 chain (28 kDa, Protein from Mus musculus)
- Myosin light chain 1/3, skeletal muscle isoform (16 kDa, Protein from Mus musculus)
- Myosin double head (Complex from Mus musculus)
- Actin (Complex from Mus musculus)
- Myosin-4 (92 kDa, Protein from Mus musculus)
- Myosin regulatory light chain 2, skeletal muscle isoform (16 kDa, Protein from Mus musculus)
- Actin, alpha skeletal muscle (41 kDa, Protein from Mus musculus)
- In situ actomyosin complex in the rigor state from mouse psoas muscle (Complex from Mus musculus)
Smooth muscle myosin shutdown state heads region
Resolution: 6.3 Å
EM Method: Single-particle
Fitted PDBs: 6z47
Q-score: 0.155
Scarff CA, Carrington G, Casas-Mao D, Chalovich JM, Knight PJ, Ranson NA, Peckham M
Nature (2020) 588 pp. 515-520 [ DOI: doi:10.1038/s41586-020-2990-5 Pubmed: 33268888 ]
- Phosphate ion (94 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Smooth muscle myosin in the shutdown state (Complex from Meleagris gallopavo)
- Myosin light chain 9 (19 kDa, Protein from turkey)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Myosin light chain smooth muscle isoform (16 kDa, Protein from turkey)
- Myosin heavy chain 11 (229 kDa, Protein from turkey)
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 6xe9
Q-score: 0.266
Yang S, Tiwari P, Lee KH, Sato O, Ikebe M, Padron R, Craig R
Nature (2020) 588 pp. 521-525 [ Pubmed: 33268893 DOI: doi:10.1038/s41586-020-3007-0 ]
- Myosin light chain 9 (19 kDa, Protein from Meleagris gallopavo)
- Smooth muscle myosin ii (530 kDa, Complex from Meleagris gallopavo)
- Myosin light chain smooth muscle isoform (16 kDa, Protein from Meleagris gallopavo)
- Myosin ii heavy chain (smooth muscle) (229 kDa, Protein from Meleagris gallopavo)
Resolution: 3.8 Å
EM Method: Helical reconstruction
Fitted PDBs: 7jh7
Q-score: 0.308
Risi C, Schafer LU, Belknap B, Pepper I, White HD, Schroder GF, Galkin VE
Structure (2021) 29 pp. 50- [ Pubmed: 33065066 DOI: doi:10.1016/j.str.2020.09.013 ]
- Magnesium ion (24 Da, Ligand)
- Myosin-7 (223 kDa, Protein from Sus scrofa)
- Actin, alpha cardiac muscle 1 (42 kDa, Protein from Sus scrofa)
- Tropomyosin (11 kDa, Protein from Sus scrofa)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Porcine native cardiac thin filament decorated with porcine cardiac myosin-s1 (492 MDa, Complex from Sus scrofa)
Cryo-EM structure of human TorsinA filament
Resolution: 4.4 Å
EM Method: Helical reconstruction
Fitted PDBs: 6oif
Q-score: 0.221
Demircioglu FE, Zheng W, McQuown AJ, Maier NK, Watson N, Cheeseman IM, Denic V, Egelman EH, Schwartz TU
Nat Commun (2019) 10 pp. 3262-3262 [ DOI: doi:10.1038/s41467-019-11194-w Pubmed: 31332180 ]
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Torsin-1a (32 kDa, Protein from Homo sapiens)
- Torsina (Complex from Homo sapiens)